The association between maternal cadmium exposure and small for gestational age: a systematic review and meta-analysis
| Autor: | Mostafa Abyareh, Ahmad Habibian Sezavar, Peter Nyasulu, Reza Fahimi, Morteza Abyadeh |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Health
Toxicology and Mutagenesis chemistry.chemical_element Physiology Gestational Age macromolecular substances medicine Humans Prospective Studies reproductive and urinary physiology Cadmium business.industry Public Health Environmental and Occupational Health Infant Newborn General Medicine medicine.disease Pollution CADMIUM EXPOSURE chemistry Maternal Exposure Meta-analysis Infant Small for Gestational Age Small for gestational age Observational study Female business |
| Zdroj: | International journal of environmental health research. 32(7) |
| ISSN: | 1369-1619 |
| Popis: | Several observational studies have found an association between maternal Cadmium (Cd) exposure and Small for Gestational Age (SGA). However, these findings are inconsistent. We conducted this meta-analysis to evaluate the relationship between maternal cadmium exposure and SGA risk. A comprehensive search was performed through PubMed, Scopus, Embase, Web of Science, Cochrane Library and OpenGrey to retrieve all pertinent studies published before October 2020. A combined odds ratio (OR) and corresponding 95% confidence interval (CI) were employed to examine this correlation. As a result, nine eligible studies met the inclusion criteria and were included in a systematic review, of those six studies containing sample type of blood were included in meta-analysis, and present meta-analysis showed that maternal cadmium exposure increased the risk of SGA 1.31 times (OR = 1.31; 95% CI = 1.16-1.47 for highest versus lowest category of cadmium). This meta-analysis suggests that maternal Cd exposure may be a risk factor for SGA. However, large prospective studies from different ethnic populations with consideration of other influencing parameters are needed to confirm this finding. |
| Databáze: | OpenAIRE |
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