The incidence of Arnold–Chiari malformation in neurological practice

Autor: I. G. Strotskaya, E. A. Shapovalova, E. A. Kantimirova, N. E. Dutova, M. M. Petrova, N. A. Shnaider, O. V. Alekseeva
Rok vydání: 2015
Předmět:
Zdroj: Nevrologiâ, Nejropsihiatriâ, Psihosomatika, Vol 7, Iss 4, Pp 18-22 (2016)
ISSN: 2310-1342
2074-2711
Popis: Arnold-Chiari malformation (ACM) is a group of congenital hindbrain malformations affecting the structural relationships between the cerebellum, brain stem, top cervical spinal cord, and bones of the skull base. In clinical practice, ACM types 0 and 1 are more common and types 2, 3, and 4 belong to rare severe (often fatal) congenital malformations. Objective: to study gender differences in the incidence of ACM types 0 and 1 in outpatient neurological practice. Patients and methods. A total 2039 case records of outpatients who had visited a neurologist of the Krasnoyarsk University clinic in 2008–2014 were analyzed. Neurological and neuroradiological (1.5 Tesla brain magnetic resonance imaging, phase-contrast spinal cerebral fluid flow imaging) diagnostic techniques were used. 3.4% (70/2039) of cases were randomized according to the criteria of inclusion and exception. An entire sample included 70 ACM patients (median age, 25 [17; 34] years) (30 (42.8–7.1%) men and 40 (57.2–7.1%) women). Results. There was an increase in the incidence of ACM type 1 in the women than in the men. Conclusion. It is necessary to develop a new strategy for the prophylactic medical examination of patients with ACM to improve primary and specialized outpatient health care.
Databáze: OpenAIRE