High-intensity Focused Ultrasound Treatment in Moderate Glaucoma Patients: Results of a 2-Year Prospective Clinical Trial
| Autor: | Ifat Sher, Ygal Rotenstreich, Yair Rubinstein, Ari Leshno, Shlomo Melamed, Reut Singer, Alon Skaat |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Intraocular pressure medicine.medical_specialty genetic structures Ophthalmic examination medicine.medical_treatment Glaucoma Slit Lamp Microscopy Tonometry Ocular 03 medical and health sciences Postoperative Complications 0302 clinical medicine medicine Humans In patient Prospective Studies Intraocular Pressure Aged Aged 80 and over business.industry Ciliary Body Ultrasound Middle Aged medicine.disease eye diseases High-intensity focused ultrasound Surgery Clinical trial Ophthalmology Treatment Outcome Positive response 030221 ophthalmology & optometry High-Intensity Focused Ultrasound Ablation Female sense organs business Glaucoma Open-Angle 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Journal of Glaucoma. 29:556-560 |
| ISSN: | 1057-0829 |
| Popis: | PRECIS Ultrasound Cyclo Plasty (UCP) treatment using high-intensity focused ultrasound (HIFU) is an effective and safe therapy to reduce intraocular pressure (IOP) in moderate glaucoma patients as was measured during a 2-year follow-up period. PURPOSE The purpose of this study was to evaluate the long-term safety and efficacy of the UCP procedure using HIFU in moderate glaucoma patients. PATIENTS AND METHODS A prospective interventional noncomparative study was carried out. Fifteen patients (15 eyes) with moderate open-angle glaucoma were enrolled. All eyes were treated with UCP-HIFU. A thorough ophthalmic examination and IOP measurements were performed before the UCP-HIFU procedure and at 1 day, 1 week, 4 weeks, 3 months, 6 months, 1 year, and 2 years after the procedure. The primary outcome was defined as a surgical success (IOP reduction of 20% or ≥5 mm Hg) at the last follow-up visit. The secondary outcomes were the mean IOP at each follow-up visit, number of medications used, complications profile, and reinterventions. RESULTS The mean preoperative IOP at baseline was 26.8±5.0 mm Hg. All patients had a positive response and a lower IOP after treatment, with a relatively stable 31% reduction in IOP during the follow-up period. A significant reduction in IOP was observed at all postprocedure examination points (P |
| Databáze: | OpenAIRE |
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