Physical activity, cardiorespiratory fitness, and metabolic outcomes in monozygotic twin pairs discordant for body mass index
| Autor: | M. Kataja, E. J. Paavonen, Aila Rissanen, Bram J. Berntzen, Nina Lundbom, Kirsi H. Pietiläinen, Antti Hakkarainen, Riitta Simonen, Jesper Lundbom, Sakari Jukarainen, Jaakko Kaprio, Päivi Piirilä, Tuija Tammelin |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Physical activity Monozygotic twin Physiology 030209 endocrinology & metabolism Physical Therapy Sports Therapy and Rehabilitation 030204 cardiovascular system & hematology Body Mass Index 03 medical and health sciences Oxygen Consumption 0302 clinical medicine Fat free mass Internal medicine Accelerometry medicine Humans Orthopedics and Sports Medicine Exercise Adiposity Metabolic health 2. Zero hunger Restless sleep Dual energy business.industry Cardiorespiratory fitness Twins Monozygotic Endocrinology Cardiorespiratory Fitness Female business human activities Body mass index |
| Zdroj: | Scandinavian Journal of Medicine & Science in Sports. 28:1048-1055 |
| ISSN: | 0905-7188 |
| DOI: | 10.1111/sms.12975 |
| Popis: | Purpose This study aims to investigate 1) how monozygotic (MZ) twin pairs who are discordant for body mass index (BMI) differ for objectively and subjectively measured physical activity (PA) and cardiorespiratory fitness (VO2max), and 2) associations of PA and VO2max with adiposity and measures of metabolic health, in individual twins and independent of genetic and shared environmental effects within twin pairs. Methods We examined 27 BMI-discordant and 14 BMI-concordant MZ twin pairs. Fat and fat free mass (ffm) were measured by dual energy x-ray absorptiometry and VO2max by spiroergometry. PA was measured objectively by accelerometers using ActiGraph GT1M for daytime activity and Actiwatch AW7 for 24h/day. Self-reported PA was obtained through the Baecke and IPAQ long-form questionnaires. Results Objectively measured moderate to vigorous PA (MVPA, min/day), steps/day and VO2max/kg were significantly lower, by 30%, 21% and 14% respectively in the heavy compared with the lean co-twins of the BMI-discordant twin pairs. There were no significant differences in self-reported PA or VO2max/ffm. As expected, PA and VO2max/ffm were similar in the BMI-concordant co-twins. Furthermore, the 24-h recording of activity suggested that the heavier co-twins had more restless sleep during the night, whereas the leaner co-twins were more active during the day. Within all twin pairs, higher MVPA and steps per day were associated with lower fat percentage and improved metabolic health measures. Conclusion Objectively, but not subjectively measured PA is associated with lower adiposity and better metabolic health, independent of genetic and shared environmental factors. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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