Evaluation for Clinical Predictors of Positive Temporal Artery Biopsy in Giant Cell Arteritis
| Autor: | Matthew J. Karban, William S. Harmsen, Tanaz A. Kermani, Kenneth J. Warrington, Kristine M. Thomsen, Kevin L. Rieck |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Fever Biopsy Giant Cell Arteritis Anti-Inflammatory Agents Vision Disorders Diagnosis Differential Prednisone Internal medicine Weight Loss medicine Humans Arteritis Glucocorticoids Aged Retrospective Studies Aged 80 and over Neck Pain Scalp medicine.diagnostic_test business.industry Headache Retrospective cohort study Odds ratio Intermittent Claudication Middle Aged medicine.disease Confidence interval Anorexia Temporal Arteries Surgery Jaw claudication Giant cell arteritis Otorhinolaryngology Polymyalgia Rheumatica Female Oral Surgery business Jaw Diseases Forecasting medicine.drug |
| Zdroj: | Journal of Oral and Maxillofacial Surgery. 69:36-40 |
| ISSN: | 0278-2391 |
| DOI: | 10.1016/j.joms.2010.02.027 |
| Popis: | Purpose To examine the clinical predictors of a positive temporal artery biopsy (TAB) among patients suspected of having giant cell arteritis. Patients and Methods We conducted a retrospective study of all consecutive patients who underwent TAB by a single surgeon (K.L.R.) at the Department of Oral Maxillofacial Surgery from April 30, 2002, to June 29, 2006. The medical records were reviewed for the clinical symptoms, laboratory findings, biopsy results, and final diagnosis. The variables of interest as predictors of positive biopsy findings were analyzed using logistic regression analysis. Results During the study period, 82 patients underwent TAB. Histologic evidence of arteritis was present in 22 patients (26.8%). Two (2.4%) were diagnosed with giant cell arteritis clinically but had negative TAB findings. The patients presenting with weight loss or jaw claudication were more likely to have a positive TAB finding (odds ratio 4.50, 95% confidence interval 1.45 to 13.93; and odds ratio 3.71, 95% confidence interval 1.28 to 10.76, respectively). No laboratory findings were predictive of a positive TAB finding. Prednisone use before TAB also was not associated with a decreased likelihood of a positive finding. Conclusions Patients suspected of having giant cell arteritis were more likely to have a positive TAB finding if they presented with weight loss or jaw claudication. In the present series, corticosteroid therapy before biopsy did not affect the rate of positive TAB findings. |
| Databáze: | OpenAIRE |
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