Changes in the activities of D-glycerate and D-3-phosphoglycerate dehydrogenases in the developing rat liver
Autor: | H.J. Sallach, Donal A. Walsh, B.E. Johnson |
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Rok vydání: | 1964 |
Předmět: |
Glycerate dehydrogenase activity
Glycerolphosphate Dehydrogenase Dehydrogenase Growth Biochemistry Fetus Pregnancy Oxidoreductase Animals Humans Glycerate dehydrogenase Phosphoglycerate Dehydrogenase chemistry.chemical_classification Phosphoglycerate kinase Research Rats Animals Newborn Liver chemistry Pregnancy Animal Female NAD+ kinase Liver function Propionates Oxidoreductases |
Zdroj: | Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 85:202-205 |
ISSN: | 0926-6569 |
DOI: | 10.1016/0926-6569(64)90241-x |
Popis: | 1. 1. The levels of activity of D -glycerate dehydrogenase ( D -glycerate: NAD (P) oxidoreductase) and D -3-phosphoglycerate dehydrogenase ( D -3-phosphoglycerate: NAD oxidoreductase) in fetal, neonatal, and adult rat liver were determined. 2. 2. On development from the fetal to the postnatal (13–17 day) stage there is an inverse relationship in the levels of activity per gram of liver of the two dehydrogenases. D -Glycerate dehydrogenase activity increases ten-fold and D -3-phosphoglycerate dehydrogenase activity decreases three-fold. Further development of the 13–17-day-old rat to the adult is marked by a decrease in the activities of both dehydrogenases. |
Databáze: | OpenAIRE |
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