Changes in the activities of D-glycerate and D-3-phosphoglycerate dehydrogenases in the developing rat liver

Autor: H.J. Sallach, Donal A. Walsh, B.E. Johnson
Rok vydání: 1964
Předmět:
Zdroj: Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 85:202-205
ISSN: 0926-6569
DOI: 10.1016/0926-6569(64)90241-x
Popis: 1. 1. The levels of activity of D -glycerate dehydrogenase ( D -glycerate: NAD (P) oxidoreductase) and D -3-phosphoglycerate dehydrogenase ( D -3-phosphoglycerate: NAD oxidoreductase) in fetal, neonatal, and adult rat liver were determined. 2. 2. On development from the fetal to the postnatal (13–17 day) stage there is an inverse relationship in the levels of activity per gram of liver of the two dehydrogenases. D -Glycerate dehydrogenase activity increases ten-fold and D -3-phosphoglycerate dehydrogenase activity decreases three-fold. Further development of the 13–17-day-old rat to the adult is marked by a decrease in the activities of both dehydrogenases.
Databáze: OpenAIRE