Invasive Pulmonary Aspergillosis in the Epidural Space in a Patient with Acute Myelogenous Leukemia with Myelodysplasia-related Changes: A Case Study and Literature Review of Vertebral Aspergillosis in Japan
| Autor: | Satomi Okada, Ryohei Ono, Shuku Sato, Yotaro Tamai, Emiko Kanbe, Eri Tanaka |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Epidural Space medicine.medical_specialty Fever Pleural effusion 030106 microbiology review Case Report vertebral aspergillosis Aspergillosis Aspergillus fumigatus 03 medical and health sciences Myelogenous Japan Internal Medicine medicine AML/MRC Humans Aged Invasive Pulmonary Aspergillosis Bronchiectasis biology business.industry General Medicine Pneumonia biology.organism_classification medicine.disease epidural mass Magnetic Resonance Imaging Epidural space Leukemia Leukemia Myeloid Acute medicine.anatomical_structure Cough Myelodysplastic Syndromes Female Spinal Diseases Radiology business Febrile neutropenia |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | Vertebral aspergillosis is a rare infectious disease with a high mortality rate. We herein report a 70-year-old woman with acute myelogenous leukemia with myelodysplasia-related changes, nontuberculous mycobacteriosis, and bronchiectasis who presented with a fever and cough. Her clinical symptoms and laboratory test results suggested febrile neutropenia and pneumonia. However, her clinical course was further complicated by lower extremity weakness. Magnetic resonance imaging of the spine showed consolidation contiguously spreading toward the epidural space between the T4 and T5. Cytological testing of the pleural effusion revealed Aspergillus fumigatus. We also review and summarize previously reported cases of vertebral aspergillosis in Japan. |
| Databáze: | OpenAIRE |
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