The role of non-stenosing carotid artery plaques in embolic stroke of undetermined source, is it a silent offender? A review of literature

Autor: Ammar Jumah, Hassan Aboul Nour, Michael Fana, Omar Choudhury, Lara Eltous, Sohaib Zoghoul, Fareed Jumah, Owais K Alsrouji, Hisham Alhajala, Osama Intikhab, Horia Marin, Alex Chebl, Daniel Miller
Rok vydání: 2022
Předmět:
Zdroj: Interventional Neuroradiology. :159101992211431
ISSN: 2385-2011
1591-0199
DOI: 10.1177/15910199221143172
Popis: Purpose Atherosclerotic cervical internal carotid artery disease is one of the major causes of ischemic stroke and transient ischemic attacks. The risk of stroke from mild to moderate stenoses (i.e. Methods We performed a literature search using PubMed, EMBASE, and Web of Science. The terms “embolic stroke of undetermined source” and “plaque morphology” were used either alone or in combination with “non-flow limiting stenosis,” “non-stenosing plaques,” “high-risk plaque features” or “internal carotid artery plaque.” Data on plaque morphology and ESUS were mainly taken from review articles, observational studies including retrospective cohort and cross-sectional studies, meta-analyses, and systematic reviews. Conclusion Nonstenosing carotid artery plaques with high-risk features carry a remarkable risk for stroke occurrence and randomized clinical trials are warranted for further evaluation of using carotid artery stenting or carotid endarterectomy to mitigate the risk of stroke.
Databáze: OpenAIRE