Functional Cationic Nanomagnet−Porphyrin Hybrids for the Photoinactivation of Microorganisms
| Autor: | João P. C. Tomé, Eliana Alves, Angela Cunha, João Rocha, José A. S. Cavaleiro, Adelaide Almeida, Zhi Lin, Maria G. P. M. S. Neves, Carla M. B. Carvalho, Liliana Vale Costa, Maria A. F. Faustino, Augusto C. Tomé |
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| Rok vydání: | 2010 |
| Předmět: |
Porphyrins
Light medicine.medical_treatment Microorganism General Physics and Astronomy Photodynamic therapy medicine.disease_cause Enterococcus faecalis Magnetics chemistry.chemical_compound Anti-Infective Agents Escherichia coli medicine Bacteriophage T4 General Materials Science Microbial Viability biology General Engineering Cationic polymerization biology.organism_classification Antimicrobial Porphyrin Combinatorial chemistry Nanostructures chemistry Biochemistry Bacteria |
| Zdroj: | ACS Nano. 4:7133-7140 |
| ISSN: | 1936-086X 1936-0851 |
| DOI: | 10.1021/nn1026092 |
| Popis: | Cationic nanomagnet-porphyrin hybrids were synthesized and their photodynamic therapy capabilities were investigated against the Gram (-) Escherichia coli bacteria, the Gram (+) Enterococcus faecalis bacteria and T4-like phage. The synthesis, structural characterization, photophysical properties, and antimicrobial activity of these new materials are discussed. The results show that these new multicharged nanomagnet-porphyrin hybrids are very stable in water and highly effective in the photoinactivation of bacteria and phages. Their remarkable antimicrobial activity, associated with their easy recovery, just by applying a magnetic field, makes these materials novel photosensitizers for water or wastewater disinfection. |
| Databáze: | OpenAIRE |
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