Final height in girls with slowly progressive untreated central precocious puberty
| Autor: | Antonio Boldrini, Paolo Ghirri, L Coccoli, M Gasperi, U Bottone, R Giovanelli, M Bernardini |
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| Rok vydání: | 1997 |
| Předmět: |
medicine.medical_specialty
Aging Body height Endocrinology Diabetes and Metabolism Idiopathic Precocious Puberty Central precocious puberty Puberty Precocious Endocrinology Animal science Internal medicine Age Determination by Skeleton medicine Precocious puberty Humans Child Ultrasonography business.industry Final height Ovary Uterus Obstetrics and Gynecology Bone age Chronological age Luteinizing Hormone medicine.disease Prognosis Body Height Female Follicle Stimulating Hormone business |
| Zdroj: | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 11(5) |
| ISSN: | 0951-3590 |
| Popis: | A group of six girls with slowly progressive idiopathic precocious puberty (IPP) and a good initial height prognosis was followed without treatment. At first observation the girls had a bone age advance over chronological age of no more than 18 months, a delta height age (delta HA): delta bone age (delta BA) ratio higher than 0.9 and height prognosis was unimpaired after 6 months. During the first two years of follow-up the girls maintained an acceptable height potential. The delta HA:delta BA ratio remained constant at greater than 0.9. Predicted height showed a slight increase or decrease (+/- 4 cm). The girls were reevaluated after the age of 14 years and followed-up until they reached their final height (FH). The mean FH (155.4 +/- 2.8 cm) was below the mean target height (159.3 +/- 4.2 cm) by 3.9 cm (range -2.1 to -6.7 cm); this difference was not statistically significant. The FH was more than 5 cm below the target height in only one case; this girl had the most precocious onset of puberty, at 6 years of age. In three cases FH was between the 3rd and 10th centiles. These three girls had a target height below 158 cm (< 25th centile). Girls with slowly progressive IPP and a good initial height prognosis preserved height potential with an acceptable final height without therapy. |
| Databáze: | OpenAIRE |
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