Prevalence of cleft lip and/or cleft palate in Guangdong province, China, 2015–2018: a spatio-temporal descriptive analysis
| Autor: | Haisheng Wu, Fenghua Liu, Huazhang Miao, Yingxian Zhu, Bing Li, Yuliang Chen, Qinghui Zeng, Pi Guo, Degang Wang, Xiaolin Yu |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Adult Male Pediatrics medicine.medical_specialty China South china Pearl river delta Epidemiology Birth weight Cleft Lip Mothers Demographic data paediatrics 03 medical and health sciences 0302 clinical medicine Pregnancy Prevalence Medicine Humans Child business.industry Infant Newborn Infant 030206 dentistry General Medicine Cleft Palate 030104 developmental biology developmental neurology & neurodisability Female business community child health |
| Zdroj: | BMJ Open, Vol 11, Iss 8 (2021) BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesThis study aimed to investigate the temporal and spatial characteristics of cleft lip and/or palate based on a large-scale birth defect monitoring database.MethodsData on perinatal infants and children with cleft lip and/or palate defects from 1 January 2015 to 31 December 2018 in Guangdong province of China were collected. The variables including the demographic data, basic family information (address, education level, etc.), the infant’s birth weight, gender and other basic parameters were collected and analysed.ResultsDuring the study period, the prevalence of cleft lip and/or palate was 7.55 per 10 000 perinatal infants. The prevalence of cleft lip, cleft palate and cleft lip and palate were 2.34/10 000, 2.22/10 000 and 2.98/10 000, respectively. The prevalence of cleft lip and/or palate showed a pronounced downward trend, reducing from 8.47/10 000 in 2015 to 6.51/10 000 in 2018. We observed spatial heterogeneity of prevalence of cleft lip and/or palate across the study period in Guangdong. In the Pearl River Delta region, the overall prevalence of cleft lip and/or palate was 7.31/10 000, while the figure (7.86/10 000) was slightly higher in the non-Pearl River Delta region (pConclusionThis study contributes a better understanding of the characteristics of spatio-temporal trends for birth defects of cleft lip and/or palate in south China. |
| Databáze: | OpenAIRE |
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