High numerical aperture tabletop soft x-ray diffraction microscopy with 70-nm resolution
Autor: | Przemyslaw Wachulak, Changyong Song, Chan La-o-vorakiat, Carmen S. Menoni, Ariel Paul, Henry C. Kapteyn, Mario C. Marconi, Jianwei Miao, Edwin A. Lee, Jorge J. Rocca, Margaret M. Murnane, Richard L. Sandberg, Anne Sakdinawat, Bagrat Amirbekian, Daisy Raymondson |
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Rok vydání: | 2008 |
Předmět: |
Optics and Photonics
Materials science Microscope Ultraviolet Rays Astrophysics::High Energy Astrophysical Phenomena RESOLFT Analytical chemistry Physics::Optics law.invention Optics X-Ray Diffraction law Image Interpretation Computer-Assisted Microscopy Nanotechnology Photoactivated localization microscopy Lenses Multidisciplinary business.industry Super-resolution microscopy Lasers Resolution (electron density) Equipment Design Physical Sciences Nanoparticles Diffraction-limited system Near-field scanning optical microscope business Algorithms |
Zdroj: | Proceedings of the National Academy of Sciences. 105:24-27 |
ISSN: | 1091-6490 0027-8424 |
DOI: | 10.1073/pnas.0710761105 |
Popis: | Light microscopy has greatly advanced our understanding of nature. The achievable resolution, however, is limited by optical wavelengths to approximately 200 nm. By using imaging and labeling technologies, resolutions beyond the diffraction limit can be achieved for specialized specimens with techniques such as near-field scanning optical microscopy, stimulated emission depletion microscopy, and photoactivated localization microscopy. Here, we report a versatile soft x-ray diffraction microscope with 70- to 90-nm resolution by using two different tabletop coherent soft x-ray sources-a soft x-ray laser and a high-harmonic source. We also use field curvature correction that allows high numerical aperture imaging and near-diffraction-limited resolution of 1.5lambda. A tabletop soft x-ray diffraction microscope should find broad applications in biology, nanoscience, and materials science because of its simple optical design, high resolution, large depth of field, 3D imaging capability, scalability to shorter wavelengths, and ultrafast temporal resolution. |
Databáze: | OpenAIRE |
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