Cortical Clefts and Cortical Bumps: A Continuous Spectrum

Autor: Ravichandran Vivekandan, Suresh Thirunavukarasu, Asthik Biswas, Farha Furruqh
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 10, Iss 7, Pp TD01-TD02 (2016)
Popis: Cortical ‘clefts’ (schizencephaly) and cortical ‘bumps’ (polymicrogyria) are malformations arising due to defects in postmigrational development of neurons. They are frequently encountered together, with schizencephalic clefts being lined by polymicrogyria. We present the case of an eight-year-old boy who presented with seizures. Imaging revealed closed lip schizencephaly, polymicrogyria and a deep ‘incomplete’ cleft lined by polymicrogyria not communicating with the lateral ventricle. We speculate that hypoperfusion or ischaemic cortical injury during neuronal development may lead to a spectrum of malformations ranging from polymicrogyria to incomplete cortical clefts to schizencephaly.
Databáze: OpenAIRE