Heart rate dynamics in refractory and well controlled temporal lobe epilepsy
| Autor: | Heikki V. Huikuri, U Tolonen, Jouko I. T. Isojärvi, Vilho V. Myllylä, Juha T. Korpelainen, Hanna Ansakorpi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
Paper
Adult Male medicine.medical_specialty Heart disease Autonomic Nervous System behavioral disciplines and activities Temporal lobe Central nervous system disease Epilepsy Death Sudden Heart Rate Risk Factors Internal medicine Heart rate medicine Humans Ictal medicine.diagnostic_test Signal Processing Computer-Assisted medicine.disease nervous system diseases Psychiatry and Mental health Autonomic nervous system Endocrinology Fractals Epilepsy Temporal Lobe Nonlinear Dynamics Cardiology Electrocardiography Ambulatory Surgery Anticonvulsants Female Neurology (clinical) Psychology Electrocardiography |
| Popis: | Objectives: Disorders of cardiovascular and other autonomic nervous system functions are often found in patients with temporal lobe epilepsy (TLE). Cardiovascular dysregulation in TLE has previously been quantified assessing traditional time and frequency domain measures of heart rate (HR) variability from short term ECG recordings. However, new complexity and fractal measures of HR variability based on non-linear dynamics and fractals ("chaos theory") may disclose certain patterns of HR dynamics that cannot be detected using only conventional measures. Methods: In addition to the traditional spectral and non-spectral components of HR variability, fractal correlation properties, approximate entropy (ApEn) of RR interval dynamics, and the slope of the power law relation were measured from 24 hour ambulatory ECG recordings to evaluate interictal autonomic cardiovascular regulatory function in 19 patients with refractory TLE, 25 patients with well controlled TLE, and in 34 healthy age and sex matched control subjects. Results: The traditional time and frequency domain measures were lower in patients with TLE than in controls (p |
| Databáze: | OpenAIRE |
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