Noise-aided logic in an electronic analog of synthetic genetic networks
Autor: | Syamal K. Dana, Elizabeth Kehler, Sudeshna Sinha, Edward H. Hellen, Ju¨ rgen Kurths |
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Rok vydání: | 2013 |
Předmět: |
Diode–transistor logic
Computer science Molecular Networks (q-bio.MN) lcsh:Medicine NAND gate FOS: Physical sciences law.invention Boolean algebra symbols.namesake law Computer Science::Logic in Computer Science Quantitative Biology - Molecular Networks Gene Regulatory Networks Physics - Biological Physics lcsh:Science Register-transfer level Logic optimization Electronic circuit Digital electronics Multidisciplinary Sequential logic business.industry lcsh:R Logic family NOR logic Logic level Biological Physics (physics.bio-ph) Logic gate Electrical network FOS: Biological sciences symbols lcsh:Q business Algorithm Asynchronous circuit Hardware_LOGICDESIGN Research Article |
Zdroj: | PLoS ONE PLoS ONE, Vol 8, Iss 10, p e76032 (2013) |
ISSN: | 1932-6203 |
Popis: | We report the experimental verification of noise-enhanced logic behaviour in an electronic analog of a synthetic genetic network, composed of two repressors and two constitutive promoters. We observe good agreement between circuit measurements and numerical prediction, with the circuit allowing for robust logic operations in an optimal window of noise. Namely, the input-output characteristics of a logic gate is reproduced faithfully under moderate noise, which is a manifestation of the phenomenon known as Logical Stochastic Resonance. The two dynamical variables in the system yield complementary logic behaviour simultaneously. The system is easily morphed from AND/NAND to OR/NOR logic. 14 pages, 7 figures. Submitted. Revised 16 pages, 9 figures |
Databáze: | OpenAIRE |
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