Prevalence of IgG Antibodies against Borrelia Burgdorferi S.L. and Ehrlichia Phagocytophila in Sera of Patients Presenting Symptoms of Lyme Disease in a Central Region of Italy

Autor: Rosa Sessa, Daniela Santapaola, D. Speziale, Mauro Nicoletti, Iolanda Santino, M. Del Piano, Guido Fadda, R. Grillo
Rok vydání: 2002
Předmět:
Zdroj: International Journal of Immunopathology and Pharmacology. 15:245-248
ISSN: 2058-7384
DOI: 10.1177/039463200201500313
Popis: The aim of this study was to evaluate the prevalence (seroprevalence) of antibodies against Borrelia burgdorferi and Ehrlichia phagocytophila among patients resident in Lazio, a region of central Italy. Of a sample of 1,050 patients, which presented clinical manifestations related to Lyme disease, 34 (3.2%) were Borrelia-seropositive (Lyme index value ≥ 1.2). The sera of 25 out of the 34 patients that were Borrelia-positive were also analysed for the presence of antibodies against E. phagocytophila and 3 (12%) were found Ehrlichia-positive (titres >1:64). No Ehrlichia-positive samples were found among sera of 250 Borrelia-negative patients. Since both B. burgdorferi s.l. and Ehrlichia species share the same tick vector ( Ixodes ricinus), our results indicate that concurrent transmission of these microbial pathogens might have been occurred among the patients included in this study.
Databáze: OpenAIRE