Anti-depressive treatment in Parkinson's disease A CONTROLLED TRIAL OF THE EFFECT OF NORTRIPTYLINE IN PATIENTS WITH PARKINSON'S DISEASE TREATED WITH L-DOPA
| Autor: | E. Aabro, A. Hjelmsted, H. E. Pedersen, J. Andersen, N. Gulmann |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Parkinson's disease Nortriptyline Disease Placebo law.invention Levodopa Double-Blind Method Randomized controlled trial law Internal medicine medicine Humans Depression (differential diagnoses) Aged Clinical Trials as Topic Depression business.industry Parkinsonism Therapeutic effect Parkinson Disease General Medicine Middle Aged medicine.disease Neurology Anesthesia Drug Therapy Combination Female Neurology (clinical) business medicine.drug |
| Zdroj: | Acta Neurologica Scandinavica. 62:210-219 |
| ISSN: | 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1980.tb03028.x |
| Popis: | Nineteen patients with L-DOPA treated parkinsonism involving depressive symptoms, the therapeutic effect of nortriptyline was compared to placebo in a controlled trial. The depressive and neurological symptoms were evaluated by rating scales. Nortriptyline had a clinical significant effect with regard to the depressive symptoms, whereas the neurological parameters were unchanged. The authors suggest the depression in Parkinson's disease to be of both reactive and endogenous origins. |
| Databáze: | OpenAIRE |
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