Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
| Autor: | M. Jiménez, Eric S. Halsey, V. Alberto Laguna-Torres, Melvin Barrantes, Wilson Chicaiza, Ivette Lorenzana de Rivera, Josefina Garcia, Roberto Agudo, Jorge Gomez, Felix Sanchez, Ana E. Arango, Tadeusz J. Kochel, Guillermo Comach, Merly Sovero |
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| Rok vydání: | 2011 |
| Předmět: |
Viral Diseases
Epidemiology Sequence analysis Gene Identification and Analysis lcsh:Medicine Biology Infectious Disease Epidemiology Virus Cell Line Molecular Genetics Antigen Phylogenetics Genotype Genetics Animals Humans lcsh:Science Gene Phylogeny DNA Primers Respiratory Syncytial Virus Infection Genetic diversity Multidisciplinary Base Sequence Respiratory tract infections Reverse Transcriptase Polymerase Chain Reaction lcsh:R Central America South America Virology Respiratory Syncytial Viruses Infectious Diseases Genetic Epidemiology Medicine lcsh:Q Research Article |
| Zdroj: | PLoS ONE, Vol 6, Iss 8, p e22111 (2011) PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0022111 |
| Popis: | Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2. |
| Databáze: | OpenAIRE |
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