Acute lumbar polyradiculoneuropathy as early sign of methotrexate intrathecal neurotoxicity: Case report and literature review

Autor: Jordi Casanova-Molla, Carmen Montejo, G Mayà-Casalprim, Judith Navarro-Otano, Michela Campolo
Rok vydání: 2019
Předmět:
Zdroj: Clinical Case Reports
Clinical Case Reports, Vol 7, Iss 4, Pp 638-643 (2019)
ISSN: 2050-0904
Popis: Key Clinical Message Acute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination. The absence of lumbosacral F waves motor responses without demyelinating findings may indicate early direct root toxicity. Early electromyography (EMG) screening could be a valuable tool for detecting peripheral neurotoxicity.
Databáze: OpenAIRE
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