Phosphoglucose isomerase gene duplication in the bony fishes: An evolutionary history
| Autor: | Kitto Gb, John C. Avise |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Protein Denaturation
Glucose-6-phosphate isomerase Hot Temperature Electrophoresis Starch Gel Cyprinidae Biochemistry Isozyme Genome Species Specificity Gene duplication Genetics Animals Molecular Biology Gene Ecology Evolution Behavior and Systematics biology Muscles Structural gene Fishes Glucose-6-Phosphate Isomerase General Medicine biology.organism_classification Biological Evolution Phenotype Isoenzymes Kinetics Genes Spectrophotometry Ultraviolet lipids (amino acids peptides and proteins) Salmonidae |
| Zdroj: | Biochemical Genetics. 8:113-132 |
| ISSN: | 1573-4927 0006-2928 |
| DOI: | 10.1007/bf00485540 |
| Popis: | Electrophoretic patterns of phosphoglucose isomerase (PGI) in bony fishes provide strong evidence for a model of genetic control by two independent structural gene loci, most likely resulting from a gene duplication. This model is confirmed by a comparison of certain kinetic and molecular properties of the PGI homodimers (PGI-1 and PGI-2) isolated from extracts of the teleost Astyanax mexicanus. In addition, in most higher teleosts examined, the PGI enzymes show a regular pattern of tissue distribution, with PGI-2 predominant in muscle, the heterodimer often strongest in the heart, and PGI-1 predominant in liver and other organs. An examination of 53 species of bony fishes belonging to 38 families indicates a widespread occurrence of duplicate PGI loci and an early origin of the gene duplication, perhaps in the Leptolepiformes. The apparent presence of three PGI loci in trout and goldfish exemplifies how new loci can be incorporated into the genome through polyploidization. |
| Databáze: | OpenAIRE |
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