Burst Stimulation Improves Hemodynamics During Resuscitation After Prolonged Ventricular Fibrillation
| Autor: | Sharon B. Melnick, Cheryl R. Killingsworth, Raymond E. Ideker, Gregory P. Walcott |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Time Factors Swine Defibrillation medicine.medical_treatment Electric Countershock Blood Pressure Return of spontaneous circulation Autonomic Nervous System Ventricular Function Left Article Electrocardiography Physiology (medical) Ventricular Pressure medicine Animals Cardiopulmonary resuscitation business.industry Hemodynamics Heart Sudden cardiac arrest medicine.disease Cardiopulmonary Resuscitation Pulse pressure Disease Models Animal Treatment Outcome Blood pressure Anesthesia Ventricular Fibrillation Ventricular fibrillation Ventricular pressure Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Circulation: Arrhythmia and Electrophysiology. 2:57-62 |
| ISSN: | 1941-3084 1941-3149 |
| DOI: | 10.1161/circep.108.799890 |
| Popis: | Background— Although return of spontaneous circulation is frequently achieved during resuscitation for sudden cardiac arrest, systolic blood pressure can then decrease, requiring additional myocardial support. Previous studies have shown that a series of 1-ms electric pulses delivered through the defibrillation patches during ventricular fibrillation can stimulate the autonomic nervous system to increase myocardial function after defibrillation. We hypothesized that a similar series of electric pulses could increase myocardial function and blood pressure during the early postresuscitation period. Methods and Results— Six swine were studied that underwent 6 to 7 minutes of fibrillation. Each animal received 5, 10, 15, or 20 pulse packets consisting of six 10-A, 1-ms pulses every 3 to 4 s in random order whenever systolic blood pressure became Conclusions— Electric stimulation during regular rhythm after prolonged ventricular fibrillation and resuscitation can increase blood pressure and cardiac function to above prestimulation levels. |
| Databáze: | OpenAIRE |
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