Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery
Autor: | Birgitte Vrou Offersen, Lisbet Rosenkrantz Hölmich, Anne Bodilsen, Peer Christiansen, Rob A. E. M. Tollenaar, M.B. Jensen, E. Heeg, Bent Ejlertsen, Marc A.M. Mureau, Anne-Vibeke Lænkholm |
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Přispěvatelé: | Plastic and Reconstructive Surgery and Hand Surgery |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Databases
Factual medicine.medical_treatment Denmark Mastectomy Segmental THERAPY DOT 4 0302 clinical medicine Breast-conserving surgery 030212 general & internal medicine Breast Mastectomy Aged 80 and over education.field_of_study OUTCOMES Carcinoma Ductal Breast Middle Aged CONSERVATION SURGERY CANCER SURGERY Treatment Outcome 030220 oncology & carcinogenesis RADICAL-MASTECTOMY Original Article Female RADIOTHERAPY Adult Reoperation medicine.medical_specialty Population Breast Neoplasms Lower risk 03 medical and health sciences medicine Humans education Propensity Score Radical mastectomy Aged business.industry 20-YEAR FOLLOW-UP Original Articles REOPERATION RATES Surgery Oncoplastic Surgery Carcinoma Lobular Logistic Models Propensity score matching Multivariate Analysis PRACTICE GUIDELINE business Follow-Up Studies SINGLE-INSTITUTION |
Zdroj: | Heeg, E, Jensen, M B, Holmich, L R, Bodilsen, A, Tollenaar, R A E M, Laenkholm, A V, Offersen, B V, Ejlertsen, B, Mureau, M A M & Christiansen, P M 2020, ' Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery : a nationwide population-based study ', British Journal of Surgery, vol. 107, no. 13, pp. 1762-1772 . https://doi.org/10.1002/bjs.11838 British Journal of Surgery, 107(13), 1762-1772. John Wiley & Sons Ltd. The British Journal of Surgery British Journal of Surgery, 107(13), 1762-1772. WILEY British Journal of Surgery, 107(13), 1762-1772. Oxford University Press Heeg, E, Jensen, M B, Hölmich, L R, Bodilsen, A, Tollenaar, R A E M, Lænkholm, A V, Offersen, B V, Ejlertsen, B, Mureau, M A M & Christiansen, P M 2020, ' Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery : a nationwide population-based study ', British Journal of Surgery, vol. 107, no. 13, pp. 1762-1772 . https://doi.org/10.1002/bjs.11838 |
ISSN: | 0007-1323 |
Popis: | Background There is no consensus regarding the impact of oncoplastic surgery (OPS) on rates of re‐excision and conversion to mastectomy following breast‐conserving surgery (BCS). Here these two outcomes after BCS and OPS were compared in a nationwide population‐based setting. Methods In Denmark, all OPS is registered and categorized into volume displacement, volume reduction or volume replacement. Patients who underwent BCS or OPS between 2012 and 2018 were selected from the Danish Breast Cancer Group database. Multivariable analyses were performed to adjust for confounders, and propensity score matching to limit potential confounding by indication bias. Results A total of 13 185 patients (72·5 per cent) underwent BCS and 5003 (27·5 per cent) OPS. Volume displacement was used in 4171 patients (83·4 per cent), volume reduction in 679 (13·6 per cent) and volume replacement in 153 (3·1 per cent). Re‐excision rates were 15·6 and 14·1 per cent after BCS and OPS respectively. After adjusting for confounders, patients were less likely to have a re‐excision following OPS than BCS (odds ratio (OR) 0·80, 95 per cent c.i. 0·72 to 0·88), specifically after volume displacement and reduction. The rate of conversion to mastectomy was similar after OPS and BCS (3·2 versus 3·7 per cent; P = 0·105), but with a lower risk in adjusted analysis (OR 0·69, 0·58 to 0·84), specifically after volume displacement and reduction procedures. Findings were similar after propensity score matching. Conclusion A modest decrease in re‐excision rate and less frequent conversion to mastectomy were observed after OPS compared with BCS. Compared with breast‐conserving surgery, oncoplastic surgery results in a modest decrease in re‐excision rates and less frequent conversion to mastectomy. Rates similar to breast‐conserving surgery only |
Databáze: | OpenAIRE |
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