Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery

Autor: Birgitte Vrou Offersen, Lisbet Rosenkrantz Hölmich, Anne Bodilsen, Peer Christiansen, Rob A. E. M. Tollenaar, M.B. Jensen, E. Heeg, Bent Ejlertsen, Marc A.M. Mureau, Anne-Vibeke Lænkholm
Přispěvatelé: Plastic and Reconstructive Surgery and Hand Surgery
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Databases
Factual
medicine.medical_treatment
Denmark
Mastectomy
Segmental
THERAPY
DOT 4
0302 clinical medicine
Breast-conserving surgery
030212 general & internal medicine
Breast
Mastectomy
Aged
80 and over
education.field_of_study
OUTCOMES
Carcinoma
Ductal
Breast
Middle Aged
CONSERVATION SURGERY
CANCER SURGERY
Treatment Outcome
030220 oncology & carcinogenesis
RADICAL-MASTECTOMY
Original Article
Female
RADIOTHERAPY
Adult
Reoperation
medicine.medical_specialty
Population
Breast Neoplasms
Lower risk
03 medical and health sciences
medicine
Humans
education
Propensity Score
Radical mastectomy
Aged
business.industry
20-YEAR FOLLOW-UP
Original Articles
REOPERATION RATES
Surgery
Oncoplastic Surgery
Carcinoma
Lobular
Logistic Models
Propensity score matching
Multivariate Analysis
PRACTICE GUIDELINE
business
Follow-Up Studies
SINGLE-INSTITUTION
Zdroj: Heeg, E, Jensen, M B, Holmich, L R, Bodilsen, A, Tollenaar, R A E M, Laenkholm, A V, Offersen, B V, Ejlertsen, B, Mureau, M A M & Christiansen, P M 2020, ' Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery : a nationwide population-based study ', British Journal of Surgery, vol. 107, no. 13, pp. 1762-1772 . https://doi.org/10.1002/bjs.11838
British Journal of Surgery, 107(13), 1762-1772. John Wiley & Sons Ltd.
The British Journal of Surgery
British Journal of Surgery, 107(13), 1762-1772. WILEY
British Journal of Surgery, 107(13), 1762-1772. Oxford University Press
Heeg, E, Jensen, M B, Hölmich, L R, Bodilsen, A, Tollenaar, R A E M, Lænkholm, A V, Offersen, B V, Ejlertsen, B, Mureau, M A M & Christiansen, P M 2020, ' Rates of re-excision and conversion to mastectomy after breast-conserving surgery with or without oncoplastic surgery : a nationwide population-based study ', British Journal of Surgery, vol. 107, no. 13, pp. 1762-1772 . https://doi.org/10.1002/bjs.11838
ISSN: 0007-1323
Popis: Background There is no consensus regarding the impact of oncoplastic surgery (OPS) on rates of re‐excision and conversion to mastectomy following breast‐conserving surgery (BCS). Here these two outcomes after BCS and OPS were compared in a nationwide population‐based setting. Methods In Denmark, all OPS is registered and categorized into volume displacement, volume reduction or volume replacement. Patients who underwent BCS or OPS between 2012 and 2018 were selected from the Danish Breast Cancer Group database. Multivariable analyses were performed to adjust for confounders, and propensity score matching to limit potential confounding by indication bias. Results A total of 13 185 patients (72·5 per cent) underwent BCS and 5003 (27·5 per cent) OPS. Volume displacement was used in 4171 patients (83·4 per cent), volume reduction in 679 (13·6 per cent) and volume replacement in 153 (3·1 per cent). Re‐excision rates were 15·6 and 14·1 per cent after BCS and OPS respectively. After adjusting for confounders, patients were less likely to have a re‐excision following OPS than BCS (odds ratio (OR) 0·80, 95 per cent c.i. 0·72 to 0·88), specifically after volume displacement and reduction. The rate of conversion to mastectomy was similar after OPS and BCS (3·2 versus 3·7 per cent; P = 0·105), but with a lower risk in adjusted analysis (OR 0·69, 0·58 to 0·84), specifically after volume displacement and reduction procedures. Findings were similar after propensity score matching. Conclusion A modest decrease in re‐excision rate and less frequent conversion to mastectomy were observed after OPS compared with BCS.
Compared with breast‐conserving surgery, oncoplastic surgery results in a modest decrease in re‐excision rates and less frequent conversion to mastectomy. Rates similar to breast‐conserving surgery only
Databáze: OpenAIRE
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