Orienting the Pore Morphology of Core-Shell Magnetic Mesoporous Silica with the Sol-Gel Temperature. Influence on MRI and Magnetic Hyperthermia Properties
| Autor: | Geoffrey Cotin, Philippe Choquet, Paula Duenas-Ramirez, Alexandre Adam, Pierre-Emmanuel Zorn, Clémence Nadal, Damien Mertz, Sylvie Begin-Colin, Ksenia Parkhomenko |
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| Přispěvatelé: | Institut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Materials science
Morphology (linguistics) Pharmaceutical Science Nanoparticle 02 engineering and technology [CHIM.THER]Chemical Sciences/Medicinal Chemistry 010402 general chemistry 01 natural sciences Article Analytical Chemistry Nanomaterials lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry Drug Discovery MRI contrast agents mesoporous silica magnetic hyperthermia Particle Size Physical and Theoretical Chemistry Sol-gel Drug Carriers Organic Chemistry Temperature magnetic nanomaterials [CHIM.MATE]Chemical Sciences/Material chemistry Hydrogen-Ion Concentration Mesoporous silica Silicon Dioxide 021001 nanoscience & nanotechnology Magnetic Resonance Imaging 0104 chemical sciences Magnetic hyperthermia chemistry Chemical engineering Chemistry (miscellaneous) Nanoparticles Molecular Medicine 0210 nano-technology Porous medium Porosity Iron oxide nanoparticles |
| Zdroj: | Molecules Molecules, MDPI, 2021, 26 (4), pp.971. ⟨10.3390/molecules26040971⟩ Molecules, Vol 26, Iss 971, p 971 (2021) Volume 26 Issue 4 |
| ISSN: | 1420-3049 |
| DOI: | 10.3390/molecules26040971⟩ |
| Popis: | International audience; The controlled design of robust, well reproducible, and functional nanomaterials made according to simple processes is of key importance to envision future applications. In the field of porous materials, tuning nanoparticle features such as specific area, pore size and morphology by adjusting simple parameters such as pH, temperature or solvent is highly needed. In this work, we address the tunable control of the pore morphology of mesoporous silica (MS) nanoparticles (NPs) with the sol-gel reaction temperature (Tsg). We show that the pore morphology of MS NPs alone or of MS shell covering iron oxide nanoparticles (IO NPs) can be easily tailored with Tsg orienting either towards stellar (ST) morphology (large radial pore of around 10 nm) below 80 °C or towards a worm-like (WL) morphology (small randomly oriented pores channel network, of 3–4 nm pore size) above 80 °C. The relaxometric and magnetothermal features of IO@STMS or IO@WLMS core shell NPs having respectively stellar or worm-like morphologies are compared and discussed to understand the role of the pore structure for MRI and magnetic hyperthermia applications. |
| Databáze: | OpenAIRE |
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