Substituted 2-(Cyanomethyl-amino)-acetamides by a Novel Three-Component Reaction

Autor:	Dirk Behnke, Eberhardt Herdtweck, Sven Nerdinger, Katrin Illgen, Roswitha Taube
Rok vydání:	2004
Předmět:	chemistry.chemical_classification Acetic acid chemistry.chemical_compound Primary (chemistry) Chemistry Component (thermodynamics) Organic Chemistry Organic chemistry Ugi reaction General Medicine Combinatorial chemistry Amino acid
Zdroj:	Synlett. :688-692
ISSN:	1437-2096 0936-5214
Popis:	A novel three-component, one-pot reaction between primary (S)-amino acid amides, aldehydes and isocyanides in the presence of acetic acid yielding substituted 2-(cyanomethylamino)-acetamides 4 in good yields, is described. First efforts to investigate the mechanism of this reaction were undertaken.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289bb6257bb7d09d655eb3fe108dae73 https://doi.org/10.1055/s-2004-817764 Zobrazit plný text záznamu