Association between gallstone and cardio‑cerebrovascular disease: Systematic review and meta‑analysis
| Autor: | Lili Wang, Xin‑Juan Yu, Guang‑Jun Shi, Shou‑Feng Zhao, Ai‑Min Wang, Xiao‑Na Xu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Cancer Research medicine.medical_specialty cardio-cerebrovascular disease Subgroup analysis Disease Cochrane Library 03 medical and health sciences 0302 clinical medicine Immunology and Microbiology (miscellaneous) Internal medicine Medicine cardiovascular diseases subgroup analysis business.industry Incidence (epidemiology) Hazard ratio Articles General Medicine Odds ratio Confidence interval meta-analysis 030104 developmental biology 030220 oncology & carcinogenesis Meta-analysis gallstone disease business |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-1015 1792-0981 |
| Popis: | Increasing evidence connects gallstone disease (GD) to cardio-cerebrovascular disease (CVD). The aim of the present systematic review and meta-analysis was to determine whether and to what extent an association between GD and CVD existed. PubMed, EMBASE and the Cochrane Library were systemically searched up to March 3rd, 2018. A total of 10 studies (1,272,177 participants; 13,833 records; 5 prospective cohorts and 5 retrospective cohorts) were included. It was demonstrated that GD was associated with an increased risk of incidence [hazard ratio=1.24, 95% (CI) confidence interval: 1.17–1.31] and prevalence (unadjusted odds ratio=1.23, 95% CI: 1.21–1.25) of CVD. In conclusion, the presence of GD was associated with an increased risk of CVD incidence and prevalence. The association may be influenced by age and sex. These findings suggest that individuals identified with cardio-cerebrovascular disease should be evaluated for GD. |
| Databáze: | OpenAIRE |
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