Early visual changes in diabetic patients with no retinopathy measured by color discrimination and electroretinography
| Autor: | Claudia Feitosa-Santana, Mauro Nishi, Dora Fix Ventura, M. Lago, Mirella Gualtieri |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Retina Visual perception genetic structures medicine.diagnostic_test Color vision General Neuroscience Retinal Diabetic retinopathy medicine.disease eye diseases VISÃO (TRATAMENTO) chemistry.chemical_compound Neuropsychology and Physiological Psychology medicine.anatomical_structure chemistry Ophthalmology medicine sense organs Psychology Erg Retinopathy Electroretinography |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 1983-3288 1984-3054 |
| Popis: | visual changes caused by diabetes include color vision losses and an abnormal full-field electroretinogram. The purpose of this study was to evaluate color vision in type 2 diabetic patients with no clinically detectable retinopathy using an objective psychophysical color vision test, evaluate retinal function assessed by full-field electroretinography ( ff ERG), and verify the agreement among the changes detected by each of these tests. Color vision was tested and ff ERG was performed in 34 diabetic patients (20 males; ages 56 ± 9 years). Results were compared with those obtained from age-matched control groups. Color discrimination losses occurred in all three color-confusion axes with a higher incidence on the protan axis. The full- field electroretinographic data indicated that inner retinal components (i.e., ff ERG oscillatory potentials) were more affected than outer retinal components, indicating impairment of second- and third-order retinal neurons early in the disease. Previous studies reported tritan losses as a classic color vision defect in diabetes, but our results showed that all three color-confusion axes (i.e., protan, deutan, and tritan) are compromised, at least during the very early stages of the disease, reflecting a diffuse pattern of color vision loss. The full-field electroretinographic results that showed abnormalities of the inner retina support the color vision findings. Keywords: color vision, psychophysics, diabetes mellitus, diabetic retinopathy, electroretinogram, visual electrophysiology, visual perception. |
| Databáze: | OpenAIRE |
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