Photoelectrochemical Detection of Exosomal miRNAs by Combining Target-Programmed Controllable Signal Quenching Engineering

Autor:	Yanhu Wang, Mengchun Yang, Huihui Shi, Shenguang Ge, Xiao Wang, Jinghua Yu
Rok vydání:	2022
Předmět:	MicroRNAs Hemin Biosensing Techniques Exosomes Prognosis Analytical Chemistry
Zdroj:	Analytical Chemistry. 94:3082-3090
ISSN:	1520-6882 0003-2700
Popis:	MicroRNAs extracted from exosomes (exosomal miRNAs) have recently emerged as promising biomarkers for early prognosis and diagnosis. Thus, the development of an effective approach for exosomal miRNA monitoring has triggered extensive attention. Herein, a sensitive photoelectrochemical (PEC) biosensing platform is demonstrated for exosomal miRNA assay via the target miRNA-powered λ-exonuclease for the amplification strategy. The metal-organic framework (MOF)-decorated WO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288d4e4a01a77b5cd6fe54d3b5be62fd https://doi.org/10.1021/acs.analchem.1c04086 Zobrazit plný text záznamu