The birthdates of GABA-immunoreactive amacrine cells in the rat retina
| Autor: | Seung-Ho Han, Myung-Hoon Chun, Soon-Lim Shin, Mun-Yong Lee |
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| Rok vydání: | 1999 |
| Předmět: |
Retinal Ganglion Cells
medicine.medical_specialty Immunocytochemistry Retina Rats Sprague-Dawley chemistry.chemical_compound Pregnancy Internal medicine medicine Animals Humans Neurotransmitter Ganglion cell layer gamma-Aminobutyric Acid Cell growth General Neuroscience Immunohistochemistry Rats Cell biology medicine.anatomical_structure Endocrinology Animals Newborn Bromodeoxyuridine chemistry Inner nuclear layer GABAergic Female sense organs |
| Zdroj: | Experimental Brain Research. 128:309-314 |
| ISSN: | 0014-4819 |
| Popis: | The birthdates of GABAergic amacrine cells in the rat retina were investigated by immunocytochemistry using anti-GABA and anti-bromodeoxyuridine (BrdU) antisera. The ratio of co-localization of GABA to BrdU increased gradually from embryonic-day 13 (E13) and showed a peak value on E18 in the central retina and on E20 in the periphery. After birth, until postnatal-day 3 (P3), a few co-localized cells were observed in the inner nuclear layer (INL). However, in the peripheral retina, co-localized cells were observed in the INL and ganglion cell layer until P5. Our results suggest that the birthdates of GABA-immunoreactive cells vary, depending on cell-type and that there is a temporal lag in the GABA-immunoreactive cell production in the peripheral retina relative to the central retina. |
| Databáze: | OpenAIRE |
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