QOLEC2: a randomized controlled trial on nutritional and respiratory counseling after esophagectomy for cancer
| Autor: | Eleonora Pinto, Andrea Vianello, F Baratto, Carlo Castoro, Cristina Caberlotto, Rita Marchi, Francesco Cavallin, Ilaria Baldan, Rita Alfieri, E Saraceni, Marco Scarpa, Maria Teresa Nardi, Luca Maria Saadeh, Matteo Parotto, Matteo Cagol |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Counseling
Male Quality of life medicine.medical_specialty Esophageal Neoplasms medicine.medical_treatment media_common.quotation_subject Esophageal cancer Esophagectomy Nutritional counseling Randomized controlled trial law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine Surveys and Questionnaires medicine Hospital discharge Humans 030212 general & internal medicine Respiratory system Health Education media_common Aged business.industry Respiration Cancer Appetite Middle Aged medicine.disease Oncology 030220 oncology & carcinogenesis Female Original Article Nutrition Therapy business |
| Zdroj: | Supportive Care in Cancer |
| Popis: | Background Esophagectomy for cancer strongly impairs quality of life. The aim of this trial was to evaluate the effect of the nutritional and respiratory counseling on postoperative quality of life. Methods At hospital discharge, patients were randomized into four groups receiving respectively: nutritional and respiratory counseling, nutritional counseling alone, respiratory counseling alone, or standard care. The main endpoint was the impairment in quality of life in the first month after surgery. Linear mixed effect models were estimated to assess mean score differences (MDs) in quality of life scores. Results Patients receiving nutritional counseling reported less appetite loss (MD − 17.7, 95% CI − 32.2 to −3.3) than those not receiving nutritional counseling at 1 month after surgery. Dyspnea was similar between patients receiving vs. those not receiving respiratory counseling (MD − 3.1, 95% CI − 10.8 to 4.6). Global quality of life was clinically similar between patients receiving vs. those not receiving nutritional counseling over time (MD 0.9, 95% CI − 5.5 to 7.3), as well as in patients receiving vs. those not receiving respiratory counseling over time (MD 0.7, 95% CI − 5.9 to 7.2). Conclusions Intensive postoperative care does not affect global quality of life even if nutritional counseling reduced appetite loss. Electronic supplementary material The online version of this article (10.1007/s00520-020-05573-z) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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