Reorganization of sensory pathways after neonatal hemidecortication in rats
| Autor: | Oraphan Wanakhachornkrai, Boonyong Tantisira, Mayuree H. Tantisira, Kaoru Isa, Tatsuya Umeda, Tadashi Isa |
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| Rok vydání: | 2014 |
| Předmět: |
Dorsum
Biotinylated dextran amine Hemispherectomy Chemistry General Neuroscience Thalamus Sensory system General Medicine Anatomy Somatosensory system Rats Lesion medicine.anatomical_structure Animals Newborn nervous system Dorsal column nuclei Ganglia Spinal Neural Pathways otorhinolaryngologic diseases medicine Animals Rats Wistar medicine.symptom Brain Stem |
| Zdroj: | Neuroscience Research. 79:94-98 |
| ISSN: | 0168-0102 |
| DOI: | 10.1016/j.neures.2013.11.003 |
| Popis: | We investigated ascending somatosensory pathways in neonatally hemidecorticated rats. Injection of an anterograde tracer, biotinylated dextran amine (BDA), into the contralesional dorsal root ganglions revealed ipsilateral projections to the dorsal column nuclei (DCN) in hemidecorticated rats as well as in normal rats. Injection of BDA into the DCN on the same side revealed that while most axons projected to the contralateral thalamus, some axons were detected in the ipsilateral thalamus in hemidecorticated rats while such projections were rarely detected in normal rats. The results suggest that aberrant ipsilateral projections of DCN neurons contralateral to the lesion developed after the hemidecortication. |
| Databáze: | OpenAIRE |
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