The coronavirus disease pandemic among adult congenital heart disease patients and the lessons learnt - results of a prospective multicenter european registry
| Autor: | Francisco Javier Ruperti-Repilado, Helmut Baumgartner, Berto Bouma, Judith Bouchardy, Werner Budts, Laurence Campens, Massimo Chessa, Maria Jesús del Cerro Marin, Harald Gabriel, Pastora Gallego, Elvira Ana González, Annette Schophuus Jensen, Magalie Ladouceur, Christopher Lockhart, Berta Miranda-Barrio, Marielle Morissens, Eduardo Moreno Escobar, Agnès Pasquet, Joaquin Rueda Soriano, Annemien Elise van den Bosch, Heleen Berdina van der Zwaan, Daniel Tobler, Matthias Greutmann, Markus Schwerzmann |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Ruperti-Repilado, Francisco Javier; Baumgartner, Helmut; Bouma, Berto; Bouchardy, Judith; Budts, Werner; Campens, Laurence; Chessa, Massimo; Jesús Del Cerro Marin, Maria; Gabriel, Harald; Gallego, Pastora; González, Elvira Ana; Jensen, Annette Schophuus; Ladouceur, Magalie; Lockhart, Christopher; Miranda-Barrio, Berta; Morissens, Marielle; Escobar, Eduardo Moreno; Pasquet, Agnès; Soriano, Joaquin Rueda; Elise van den Bosch, Annemien; ... (2023). The coronavirus disease pandemic among adult congenital heart disease patients and the lessons learnt-results of a prospective multicenter european registry. International journal of cardiology. Congenital heart disease., 11(100428), p. 100428. Elsevier 10.1016/j.ijcchd.2022.100428 INTERNATIONAL JOURNAL OF CARDIOLOGY CONGENITAL HEART DISEASE |
| ISSN: | 2666-6685 |
| DOI: | 10.48350/175257 |
| Popis: | BACKGROUND: At the beginning of the COVID-19 pandemic, professionals in charge of particularly vulnerable populations, such as adult congenital heart disease (ACHD) patients, were confronted with difficult decision-making. We aimed to assess changes in risk stratification and outcomes of ACHD patients suffering from COVID-19 between March 2020 and April 2021. METHODS AND RESULTS: Risk stratification among ACHD experts (before and after the first outcome data were available) was assessed by means of questionnaires. In addition, COVID-19 cases and the corresponding patient characteristics were recorded among participating centres. Predictors for the outcome of interest (complicated disease course) were assessed by means of multivariable logistic regression models calculated with cluster-robust standard errors. When assessing the importance of general and ACHD specific risk factors for a complicated disease course, their overall importance and the corresponding risk perception among ACHD experts decreased over time. Overall, 638 patients (n = 168 during the first wave and n = 470 during the subsequent waves) were included (median age 34 years, 52% women). Main independent predictors for a complicated disease course were male sex, increasing age, a BMI >25 kg/m2, having ≥2 comorbidities, suffering from a cyanotic heart disease or having suffered COVID-19 in the first wave vs. subsequent waves. CONCLUSIONS: Apart from cyanotic heart disease, general risk factors for poor outcome in case of COVID-19 reported in the general population are equally important among ACHD patients. Risk perception among ACHD experts decreased during the course of the pandemic. ispartof: Int J Cardiol Congenit Heart Dis vol:11 pages:100428- ispartof: location:Netherlands status: published |
| Databáze: | OpenAIRE |
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