ADDA: a domain database with global coverage of the protein universe
| Autor: | Andreas Heger, Christopher Wilton, Liisa Holm, Ashwin Sivakumar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
InterPro
Protein structure database Quality Control Conserved Domain Database Simple Modular Architecture Research Tool Protein domain Biology computer.software_genre Domain (software engineering) 03 medical and health sciences User-Computer Interface 0302 clinical medicine Sequence Analysis Protein Genetics Humans Databases Protein 030304 developmental biology 0303 health sciences Internet Database Sequence database Articles Protein tertiary structure Protein Structure Tertiary computer 030217 neurology & neurosurgery Algorithms |
| Zdroj: | Nucleic Acids Research |
| ISSN: | 1362-4962 0305-1048 |
| Popis: | We used the Automatic Domain Decomposition Algorithm (ADDA) to generate a database of protein domain families with complete coverage of all protein sequences. Sequences are split into domains and domains are grouped into protein domain families in a completely automated process. The current database contains domains for more than 1.5 million sequences in more than 40 000 domain families. In particular, there are 3828 novel domain families that do not overlap with the curated domain databases Pfam, SCOP and InterPro. The data are freely available for downloading and querying via a web interface (http://ekhidna.biocenter.helsinki.fi:9801/sqgraph/pairsdb). |
| Databáze: | OpenAIRE |
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