Diagnostic Performance of Flat-Panel CT Arthrography for Cartilage Defect Detection in the Ankle Joint: Comparison With MDCT Arthrography With Gross Anatomy as the Reference Standard

Autor: Thomas Le Corroller, Vanessa Pauly, Julie Desrousseaux, David Chemouni, Pierre Champsaur, Daphné Guenoun
Přispěvatelé: Institut des Sciences du Mouvement Etienne Jules Marey (ISM), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Institute for Locomotion, Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Male
medicine.medical_specialty
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging
Radiation Dosage
Sensitivity and Specificity
Flat panel
Reference Values
Multidetector Computed Tomography
Cadaver
medicine
[SDV.MHEP.AHA]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
Humans
Single-Blind Method
X-Ray Intensifying Screens
Radiology
Nuclear Medicine and imaging

[PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph]
Arthrography
Reference standards
Aged
Aged
80 and over

business.industry
Cartilage
Reproducibility of Results
Equipment Design
General Medicine
Malleolus
3. Good health
Equipment Failure Analysis
medicine.anatomical_structure
Gross anatomy
Female
Ct arthrography
Radiology
Ankle
Cadaveric spasm
business
Cartilage Diseases
Ankle Joint
Zdroj: American Journal of Roentgenology
American Journal of Roentgenology, American Roentgen Ray Society, 2014, 203 (5), pp.1069-1074. ⟨10.2214/AJR.13.12163⟩
American Journal of Roentgenology, 2014, 203 (5), pp.1069-1074. ⟨10.2214/AJR.13.12163⟩
ISSN: 0361-803X
1546-3141
DOI: 10.2214/AJR.13.12163⟩
Popis: International audience; OBJECTIVE. The purpose of this study is to compare the diagnostic performance and radiation exposure of flat-panel CT arthrography for cartilage defect detection in the ankle joint to standard MDCT arthrography, using gross anatomy and thermoluminescent dosimetry as reference standards. MATERIALS AND METHODS. Ten cadaveric ankle specimens were obtained from individuals who had willed their bodies to science. Five milliliters of a mixture of diluted ioxaglate and saline were injected. Specimens were examined consecutively with the use of flat-panel CT and MDCT. Radiation doses of flat-panel CT and MDCT were recorded using thermoluminescent dosimeters. Flat-panel CT and MDCT arthrography examinations were blinded and randomly evaluated by two musculoskeletal radiologists in consensus. In each ankle specimen, eight cartilage areas were assessed separately: medial talar surface, medial talar trochlea, lateral talar trochlea, lateral talar surface, tibial malleolus, medial tibial plafond, lateral tibial plafond, and fibular malleolus. Findings at flat-panel CT and MDCT arthrography were compared with macroscopic assessments in 80 cartilage areas. RESULTS. For the detection of cartilage lesions, flat-panel CT showed a sensitivity of 80%, specificity of 98%, and accuracy of 94%, and MDCT arthrography showed a sensitivity of 55%, specificity of 98%, and accuracy of 88%. Flat-panel CT and MDCT arthrography showed almost perfect (kappa = 0.83) and substantial (kappa = 0.65) agreement, respectively, with anatomic examination. Radiation dose was significantly lower for flat-panel CT (mean, 2.1 mGy; range, 1.1-3.0 mGy) than for MDCT (mean, 47.2 mGy; range, 39.3-53.8 mGy) (p < 0.01). CONCLUSION. Flat-panel CT arthrography is accurate for detecting cartilage defects in the ankle joint and is an alternative to MDCT arthrography that may have better diagnostic performance and may permit the use of a lower radiation dose.
Databáze: OpenAIRE