Human fear-related motor neurocircuitry
| Autor: | Elizabeth A. Phelps, Emily Stern, Xenia Protopopescu, Tracy Butler, Almut Engelien, Luke J. Chang, Amy Cunningham-Bussel, Marc Goldstein, David Silbersweig, Daniel S. Weisholtz, James C. Root, Joseph E. LeDoux, X.-H. Xie, Qiang Chen, Jane Epstein, Hong Pan, Oliver Tuescher |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Amygdala Basal Ganglia Neural Pathways Basal ganglia Image Processing Computer-Assisted medicine Humans Fear processing in the brain Brain Mapping medicine.diagnostic_test General Neuroscience Motor Cortex Fear Galvanic Skin Response Magnetic Resonance Imaging Anticipation Oxygen Functional imaging medicine.anatomical_structure Female Primary motor cortex Psychology Functional magnetic resonance imaging Neuroscience Photic Stimulation Motor cortex |
| Zdroj: | Neuroscience. 150:1-7 |
| ISSN: | 0306-4522 |
| DOI: | 10.1016/j.neuroscience.2007.09.048 |
| Popis: | Using functional magnetic resonance imaging and an experimental paradigm of instructed fear, we observed a striking pattern of decreased activity in primary motor cortex with increased activity in dorsal basal ganglia during anticipation of aversive electrodermal stimulation in 42 healthy participants. We interpret this pattern of activity in motor neurocircuitry in response to cognitively-induced fear in relation to evolutionarily-conserved responses to threat that may be relevant to understanding normal and pathological fear in humans. |
| Databáze: | OpenAIRE |
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