Conditional survival and recurrence of remnant gastric cancer after surgical resection: A multi‐institutional study

Autor: Lisheng Cai, Qiu-Xian Chen, Kai-Qing Guo, Qi-Yue Chen, Chang-Ming Huang, Guang-Tan Lin, Jian-Wei Xie, Wei Lin, Xiantu Qiu, Chao-Hui Zheng, Long-Long Cao, Teng-Wen Li, Jia-Bin Wang, Jun Lu, Jun-Feng Zhou, Mi Lin, Qing Zhong, Qingliang He, Ping Li, Guo-Qiang Su, Dong-Bo Xu, Xue-Yi Dang, Shuang-Ming Lin, Zhi-Yu Liu, Jian-Xian Lin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Cancer Science
ISSN: 1349-7006
1347-9032
Popis: The present study was designed to evaluate the dynamic survival and recurrence of remnant gastric cancer (RGC) after radical resection and to provide a reference for the development of personalized follow‐up strategies. A total of 298 patients were analyzed for their 3‐year conditional overall survival (COS3), 3‐year conditional disease‐specific survival (CDSS3), corresponding recurrence and pattern changes, and associated risk factors. The 5‐year overall survival (OS) and the 5‐year disease‐specific survival (DSS) of the entire cohort were 41.2% and 45.8%, respectively. The COS3 and CDDS3 of RGC patients who survived for 5 years were 84.0% and 89.8%, respectively. The conditional survival in patients with unfavorable prognostic characteristics showed greater growth over time than in those with favorable prognostic characteristics (eg, COS3, ≥T3: 46.4%‐83.0%, Δ36.6% vs ≤T2: 82.4%‐85.7%, Δ3.3%; P 0.05). Time‐dependent logistic regression analysis showed that the AJCC stage independently affected recurrence within 2 years after surgery (P
Patients with RGC usually have a high likelihood of death or recurrence within 3 years after radical surgery. We developed a postoperative follow‐up model for RGC patients of different stages.
Databáze: OpenAIRE
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