Dynamic changes and multiplication rate of white blood cell count may direct the timing of cytoreduction chemotherapy during induction treatment in newly diagnosed acute promyelocytic leukemia with low‑intermediate risk
| Autor: | Fang Xu, Wen Qu, Jing Su, Yiping Liu, Lin Shi, Jingjing Wen, Hong Hu, Ya Zhang, Qiaolin Zhou |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Acute promyelocytic leukemia
Cancer Research medicine.medical_specialty medicine.medical_treatment WBC Gastroenterology chemistry.chemical_compound low-intermediate risk hemic and lymphatic diseases White blood cell Internal medicine medicine Arsenic trioxide Risk factor Chemotherapy business.industry Incidence (epidemiology) Mortality rate Cancer cytoreduction chemotherapy Articles medicine.disease APL induction treatment initiation time medicine.anatomical_structure Oncology chemistry multiplication rate business |
| Zdroj: | Molecular and Clinical Oncology |
| ISSN: | 2049-9469 2049-9450 |
| Popis: | In order to explore the optimal timing for initiating cytoreduction chemotherapy following all-trans retinoic acid plus arsenic trioxide administration, 58 newly diagnosed patients with acute promyelocytic leukemia (APL) with low-intermediate mortality risk were retrospectively analyzed. During induction treatment, white blood cell (WBC) count >4x109/l and multiplication rate of WBC |
| Databáze: | OpenAIRE |
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