Salivary Testosterone and Cortisol as Biomarkers for the Diagnosis of Sarcopenia and Sarcopenic Obesity in Community-Dwelling Older Adults
| Autor: | José Miguel Soriano, Angela Diago-Galmés, Carlos Guillamón-Escudero, Julio Fernández-Garrido, Jose M. Tenías-Burillo |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Gerontologia
Waist Activities of daily living Physiology 030209 endocrinology & metabolism community older adults cortisol Biology Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine medicine Sarcopenic obesity 030212 general & internal medicine lcsh:QH301-705.5 General Immunology and Microbiology Testosterone (patch) Salivary testosterone musculoskeletal system medicine.disease body regions lcsh:Biology (General) Sarcopenia testosterone Obesitat Biomarker (medicine) General Agricultural and Biological Sciences human activities Body mass index |
| Zdroj: | Diago-Galmés, Angela Guillamón-Escudero, Carlos Tenías Burillo, José María Soriano del Castillo, José Miguel Fernández Garrido, Julio Jorge 2021 Salivary Testosterone and Cortisol as Biomarkers for the Diagnosis of Sarcopenia and Sarcopenic Obesity in Community-Dwelling Older Adults Biology-Basel 10 2 93 Biology Volume 10 Issue 2 RODERIC. Repositorio Institucional de la Universitat de Valéncia instname Biology, Vol 10, Iss 93, p 93 (2021) |
| ISSN: | 2079-7737 |
| DOI: | 10.3390/biology10020093 |
| Popis: | Nowadays, the appearance of sarcopenia (S) or sarcopenic obesity (SO) is related to aging. According to the criteria of the European Working Group on Sarcopenia in Older People (EWGSOP), the feasibility of using salivary cortisol and testosterone levels was analyzed as diagnostic biomarkers of S or SO. One hundred and ninety non-institutionalized people aged &ge 65 years were studied, independent of the activities of daily living (ADLs) (Barthel > 60), and sociodemographic variables were determined together with criteria for the diagnosis of S and SO including grip force, lower body strength, appendicular skeletal muscle mass, physical performance, total body fat percentage, body mass index (BMI), waist circumference, and triceps skinfold, together with the levels of salivary cortisol and testosterone. Our results reflected that women presented a higher prevalence of S and SO (21.2% and 30.2%, respectively). A significant difference was observed between salivary testosterone levels and the age of the participants with differences by sex. Testosterone values in men with S and SO were significantly lower (p = 0.043 and p = 0.048, respectively), which suggests a potential use of the biomarker for diagnostic purposes. No significant differences were shown with cortisol values. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|