Participation of superoxide in luminol-dependent chemiluminescence triggered by mineral dust in rabbit alveolar macrophages
| Autor: | J. Wilhelm, P. Brzák, V. Vilím |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Immunology
Cytochrome c Group Stimulation Deferoxamine Mineral dust Ferricytochrome c Luminol law.invention Superoxide dismutase chemistry.chemical_compound Superoxides law medicine Animals Immunology and Allergy Chemiluminescence biology Chemistry Superoxide Macrophages Dust Quartz Silicon Dioxide Molecular biology Pulmonary Alveoli Pyridazines Biochemistry Luminescent Measurements biology.protein Rabbits medicine.drug |
| Zdroj: | Immunology Letters. 15:329-334 |
| ISSN: | 0165-2478 |
| DOI: | 10.1016/0165-2478(87)90137-4 |
| Popis: | Luminol-dependent chemiluminescence (CL) triggered by mineral dust in rabbit alveolar macrophages depended on superoxide production as revealed by inhibition by superoxide dismutase and ferricytochrome c. The contribution of superoxide changed in the course of CL peak between 80-20%. The effects of ferricytochrome c were concentration-dependent: both stimulation and inhibition were observed. Ferricytochrome c and desferal also inhibited CL pathway which was not superoxide-dependent. |
| Databáze: | OpenAIRE |
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