A Retrospective Comparative Study of Different Methods of Blood Management in Total Knee Replacement
Autor: | Emanouil Spiridakis, Eleni Pappa, Nikolaos Vergados, Anna Apostolopoulou, Savas Sourmelis, George Chountas |
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Rok vydání: | 2018 |
Předmět: |
Male
medicine.medical_specialty Blood transfusion Blood management Cost-Benefit Analysis medicine.medical_treatment Blood Loss Surgical Perioperative Care Blood Transfusion Autologous Hemoglobins 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Hematologic Agents medicine Humans Blood Transfusion Orthopedics and Sports Medicine Arthroplasty Replacement Knee Erythropoietin Aged Retrospective Studies 030222 orthopedics Creatinine Operative Blood Salvage business.industry Retrospective cohort study 030229 sport sciences Perioperative Middle Aged Arthroplasty Antifibrinolytic Agents Surgery Tranexamic Acid chemistry Hematinics Female business Tranexamic acid medicine.drug |
Zdroj: | The Journal of Knee Surgery. 32:995-1000 |
ISSN: | 1938-2480 1538-8506 |
Popis: | Perioperative blood management is essential to minimize allogeneic blood transfusion in total knee replacement. The effect of preoperative administration of erythropoietin, intraoperative cell saver, tranexamic acid, and restrictive transfusion strategies on allogeneic transfusion is studied in total knee replacement. A retrospective comparative study of 106 patients who underwent total knee replacement in different time periods was performed. Group A (n 1 = 45) underwent restrictive strategies of transfusion between 2009 and 2010. Group B (n 2 = 24) includes patients where erythropoietin of either 10.000 IU or 20.000 IU was given preoperatively. Patients of Group C (n 3 = 21) underwent autologous washed erythrocytes transfusion through a cell saver. Lastly, in Group D (n 4 = 15) tranexamic acid dose of 1 gr IV was given intraoperatively. The preoperative and discharge hemoglobin together with total units of blood transfusion and creatinine levels was studied. Tranexamic acid noted the least units of blood transfusion (mean = 0.82 units/patient, p |
Databáze: | OpenAIRE |
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