A distinct association of inflammatory molecules with outcomes of COVID-19 in younger versus older adults

Autor:	Jennefer Par-Young, Serhan Unlu, Gregory K. Buller, Yuliya Afinogenova, Junghee J. Shin, Insoo Kang, Sangchoon Jeon, John K. Kuster, Min Sun Shin, Yumi Kang, Richard Bucala, Michael Simonov
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty Aging Coronavirus disease 2019 (COVID-19) T cell Immunology Alpha (ethology) Severity of Illness Index Immune system Immunity Risk Factors Full Length Article Internal medicine medicine Immunology and Allergy Humans Association (psychology) Aged Inflammation Clinical outcome business.industry SARS-CoV-2 Acute-phase protein Age Factors COVID-19 Middle Aged Immune medicine.anatomical_structure Ambulatory Cytokines Female Inflammation Mediators business Human
Zdroj:	Clinical Immunology (Orlando, Fla.)
ISSN:	1521-7035
Popis:	Aging can alter immunity affecting host defense. COVID-19 has the most devastating clinical outcomes in older adults, raising the implication of immune aging in determining its severity and mortality. We investigated biological predictors for clinical outcomes in a dataset of 13,642 ambulatory and hospitalized adult COVID-19 patients, including younger (age
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286ac2853cd522ff7b4fc714386c3cfc https://pubmed.ncbi.nlm.nih.gov/34560283 Zobrazit plný text záznamu Full Text from ScienceDirect