Association of Acute Myocardial Infarction with ankylosing Spondylitis: A nationwide longitudinal cohort study
| Autor: | Chong Jin Park, Yoon Jin Choi, Inbo Han, Seil Sohn, Jung Min Choi, Kyungdo Han, Jeong Gyun Kim |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Longitudinal study Population Myocardial Infarction 030204 cardiovascular system & hematology Cohort Studies 03 medical and health sciences 0302 clinical medicine Risk Factors Physiology (medical) Internal medicine Cox proportional hazards regression medicine Humans Spondylitis Ankylosing cardiovascular diseases Myocardial infarction Longitudinal Studies Longitudinal cohort education Aged Proportional Hazards Models 030203 arthritis & rheumatology education.field_of_study Ankylosing spondylitis business.industry Incidence Hazard ratio General Medicine Middle Aged medicine.disease Confidence interval Neurology Surgery Female Neurology (clinical) business Follow-Up Studies |
| Zdroj: | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 56 |
| ISSN: | 1532-2653 |
| Popis: | Pertaining to an association between Acute Myocardial Infarction (AMI) and Ankylosing Spondylitis (AS) is sparse. The purpose of this nationwide longitudinal study was to investigate the prevalence of AMI in newly diagnosed AS patients. A total of 12,988 patients were enrolled in the AS group from January 1, 2010 to December 31, 2014 from the Korean National Health Insurance Service (NHIS). The control group consisted of 64,940 subjects according to 1:5 age-sex stratified matching. The AMI incidence rates in AS and control group were compared using the Kaplan-Meier method. The hazard ratio of AMI and the control group was estimated by Cox proportional hazards regression analyses. During a 6 year follow up, 62 patients (0.48%) in the AS group and 157 persons (0.24%) in the control group developed AMI. The hazard ratio of AMI in the AS group was 1.99 (95% confidence interval [95% CI], 1.48–2.67) after adjusting for sex and age. The hazard ratio of AMI in the AS group was 1.81 (95% CI, 1.34–2.43) after adjusting for demographics and comorbid medical disorders. The incidence rate of AMI increases in newly diagnosed AS patients. |
| Databáze: | OpenAIRE |
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