Comparison of International Therapy Guidelines with Regard to the Treatment of Malignant Catatonia
| Autor: | Lilli Hiesener, Alexander Sartorius, Viktoria Mühlbauer, Bernhard J. Connemann, Maximilian Gahr, Carlos Schönfeldt-Lecuona, Maximilian Cronemeyer |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment MEDLINE AUTONOMIC INSTABILITY Global Health 030226 pharmacology & pharmacy Scientific evidence Malignant catatonia 03 medical and health sciences Benzodiazepines 0302 clinical medicine Electroconvulsive therapy Rare Diseases medicine Global health Humans Pharmacology (medical) Intensive care medicine Electroconvulsive Therapy business.industry Catatonia General Medicine Evidence-based medicine Guideline 030227 psychiatry Psychotherapy Psychiatry and Mental health Practice Guidelines as Topic business Antipsychotic Agents |
| Zdroj: | Pharmacopsychiatry. 53(1) |
| ISSN: | 1439-0795 |
| Popis: | Objective Malignant catatonia (MC) is an extremely rare, life-threatening disorder. It is characterized by catatonic symptoms accompanied by autonomic instability, hyperthermia, and changes in laboratory values. In many cases, MC is not recognized as such. Evidence-based guidelines are essential to ensure quality of treatment, but what do current national and international guidelines recommend? Method Online search for international guidelines from English-, French-, Italian-, and German-speaking countries whose medical care meets high standards addressing the treatment of MC. These were analyzed and compared regarding statements on MC, recommendations, and strength of scientific evidence. Results Fifteen of the identified guidelines were included. Only 5 of 15 comment on the treatment of MC. As for other rare diseases, no detailed recommendations are available. Suggested therapies are limited to benzodiazepines and electroconvulsive therapy. Levels of evidence and grades of recommendation are predominantly low. Conclusion Many international guidelines do not mention MC. It is not possible to derive a clear algorithm for the treatment of MC from most current guidelines. A thorough update of most guidelines appears to be necessary. Lack of awareness and knowledge of MC among physicians and medical professionals might lead to inadequate or delayed care, worsened outcome, or death. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|