| Autor: |
Yuksel Yilmaz, Sacit Nuri Gorgel, Serkan Ozcan, Muhsin Engin Uluc, Omer Faruk Yagli, Mehmet Coskun, Yigit Akin, Osman Kose |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
EXPERIMENTAL BIOMEDICAL RESEARCH; Vol 3 No 3 (2020): Experimental Biomedical Research; 167-175 |
| ISSN: |
2618-6454 |
| DOI: |
10.30714/j-ebr.2020361052 |
| Popis: |
Aim: To investigate the accuracy of multiparametric prostate magnetic resonance imaging (mpMRI) in determining the diagnosis and treatment options of prostate cancer (PCa), and its pathology correlation. Methods: Between October 2017 and January 2018, 73 patients were subjected to an mpMRI at our clinic. Of these patients, 11 were radical prostatectomy (RP) after treatment, and four were post- radiation therapy (RT) follow-up. The remaining 58 patients were assigned to the PSA elevation and / or positive digital rectal examination (DRE) patient group in this study and their outcomes were evaluated. Results: Of the 58 patients included in the study, 13 were found to have a PI-RADS 5 on mpMRI and in 9 (90%) of 10 patients undergoing simultaneous biopsy, PCa was detected. The biopsy results of all cases evaluated as PI-RADS 1 were benign. All of the patients who were ISUP 3 and above had a PI-RADS 5. Patients with a PI-RADS score of 4 and above being ISUP 2 and above was statistically significant (p=0.011). A case had undergone a previous radical prostatectomy assessment revealed that tPSA increased to 2 ng/ml during the follow-up, and so RT was added to the treatment; although LAP was identified in the left iliac region on an mpMRI performed upon the continued increase of tPSA. During the follow-ups of the patient who had regional RT, the tPSA dropped below 0.01 ng/ml. Conclusion: The results of our study show that mpMRI can gain a new and important place in urology due to the guidance it provides in biopsies, facilitating targeted biopsy, its effectiveness in determining treatment modalities and its importance in post-PCa treatment follow-ups. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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