Piroxicam, aspirin, and gastrointestinal blood loss

Autor:	Joseph R. Bianchine, Robert R Procter, Fred B. Thomas
Rok vydání:	1982
Předmět:	Adult Male Pyridines Thiazines Piroxicam medicine.disease_cause Drug Administration Schedule law.invention Feces Blood loss law Gastroscopy medicine Humans Pharmacology (medical) Pharmacology Aspirin Clinical pharmacology business.industry Anti-Inflammatory Agents Non-Steroidal Anesthesia Drug Evaluation Irritation Gastrointestinal Hemorrhage business medicine.drug
Zdroj:	Clinical Pharmacology and Therapeutics. 32:247-252
ISSN:	1532-6535 0009-9236
DOI:	10.1038/clpt.1982.155
Popis:	A study to compare the effects of three piroxicam regimens and aspirin on fecal blood loss (FBL) was conducted among 39 healthy men. Fourteen of the subjects also underwent prestudy and poststudy gastroscopy. There was an increase in FBL after aspirin, 972 mg 4 times a day, whereas piroxicam, 20 mg once a day, 5 mg four times a day, and 10 mg four times a day induced no observable increase in fecal blood loss. There was gastroscopic evidence of irritation in the aspirin group, but not in any of the piroxicam groups. Clinical Pharmacology and Therapeutics (1982) 32, 247–252; doi:10.1038/clpt.1982.155
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2859b6985226630c1ecdff0d091407ec https://doi.org/10.1038/clpt.1982.155 Zobrazit plný text záznamu Plný text