Advancing Treatment of Pituitary Adenomas through Targeted Molecular Therapies: The Acromegaly and Cushing Disease Paradigms
| Autor: | Andrew S. Little, Elias D Simon, Michael A Mooney |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Conservative management Mini Review lcsh:Surgery 030209 endocrinology & metabolism pituitary adenoma Bioinformatics 03 medical and health sciences 0302 clinical medicine Pituitary adenoma Acromegaly medicine Disease process Excess growth hormone business.industry Cushing disease endonasal Treatment options lcsh:RD1-811 medicine.disease Cushing Disease Molecular targets transsphenoidal acromegaly Surgery business 030217 neurology & neurosurgery |
| Zdroj: | Frontiers in Surgery Frontiers in Surgery, Vol 3 (2016) |
| ISSN: | 2296-875X |
| Popis: | The current treatment of pituitary adenomas requires a balance of conservative management, surgical resection, and in select tumor types, molecular therapy. Acromegaly treatment is an evolving field where our understanding of molecular targets and drug therapies has improved treatment options for patients with excess growth hormone levels. We highlight the use of molecular therapies in this disease process and advances in this field, which may represent a paradigm shift for the future of pituitary adenoma treatment. |
| Databáze: | OpenAIRE |
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