The protective effects of simvastatin in Cadmium-Induced preosteoblast injury through Nox4
| Autor: | Ximou Huang, Baolin Li, Chongxia Huang, Du Liang, Chongbo Huang, Jiandong He |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Simvastatin chemistry.chemical_element Apoptosis Pharmacology Biochemistry Cell Line 03 medical and health sciences 0302 clinical medicine Medicine cardiovascular diseases Molecular Biology Cadmium Osteoblasts business.industry nutritional and metabolic diseases NOX4 Cell Biology 030104 developmental biology chemistry 030220 oncology & carcinogenesis lipids (amino acids peptides and proteins) business medicine.drug |
| Zdroj: | Journal of Receptors and Signal Transduction. 42:117-124 |
| ISSN: | 1532-4281 1079-9893 |
| Popis: | Cadmium (Cd) has a direct toxic effect on bones. Statins such as simvastatin have protective effects on various diseases, including on tissue injury. The current study revealed the efficacy of simvastatin on Cd-induced preosteoblast injury. Preosteoblast MC3T3-E1 cells were incubated with various doses of CdCl |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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