Exercise compliance among patients with multiple myeloma undergoing chemotherapy: a retrospective study
| Autor: | Suzanne O’Brien, Shirin M. Shallwani, Warren Sateren, Mary-Ann Dalzell |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Bone disease Anemia medicine.medical_treatment Pain medicine Population Quality of life Internal medicine Medicine Humans education Multiple myeloma Retrospective Studies Chemotherapy education.field_of_study business.industry Retrospective cohort study Middle Aged medicine.disease Exercise Therapy Oncology Physical therapy Quality of Life Female business Multiple Myeloma |
| Zdroj: | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 23(10) |
| ISSN: | 1433-7339 |
| Popis: | Multiple myeloma (MM) is often associated with osteolytic bone disease and anemia, resulting in skeletal fragility and persistent fatigue, pain, and reduced quality of life. Exercise is considered safe and beneficial for this population. Our objectives were to evaluate the extent to which MM patients undergoing chemotherapy complied with exercise recommendations and to identify factors associated with noncompliance.This retrospective study included 41 MM patients referred to a hospital-based rehabilitation program while undergoing chemotherapy. Variables collected at baseline (T1) and follow-up (T2) included: (a) demographics and medical history, (b) exercise levels (MET-hours/week), preferences and barriers, and (c) fatigue severity scores (0-10). Statistical analyses included logistic regression to identify factors associated with exercise noncompliance and t-tests and chi-squared tests to compare outcomes between the groups according to compliance.The mean age of the participants was 61 years; 73 % were male and 81 % had bone lesions. Overall exercise compliance at T2 was 71 %, with an observed increase in exercise levels (mean group difference: 6.5 MET-hours/week; p0.001) and decrease in fatigue severity scores (mean group difference -1.2; p = 0.003). Factors associated with exercise noncompliance included history of pathological fracture (odds ratio [OR] 4.7; p = 0.049), spinal cord compression (SCC) (OR 14.1; p = 0.023), and radiation (OR 28.0; p0.001).In this sample of MM patients, high compliance with exercise and associated improvements in fatigue were observed. However, participants with a history of pathological fracture, SCC, or radiation are at increased risk of noncompliance and may require additional supervision to improve exercise compliance. |
| Databáze: | OpenAIRE |
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