Regio- and stereoselective synthesis of (+)-6-ketoeuryfuran, (+)-6-ketowinterin, and (-)-7-ketoeuryfuran from accessible labdane diterpenoids (+)-larixol and (-)-sclareol
| Autor: | Carolina Edu, M. N. Coltsa, Aculina Aricu, Michele D'Ambrosio, Pavel F. Vlad, Sergiu Shova, Andrei Biriiac, Nicoleta Vornicu, Alexandru Ciocarlan, Alina Nicolescu, Calin Deleanu, Aede de Groot |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
euryfuran
(+/-)-euryfuran Stereochemistry 010402 general chemistry 01 natural sciences Biochemistry singlet oxygen Labdane sponge chemistry.chemical_compound ring transfer-reaction Drug Discovery photooxygenation Organic chemistry 010405 organic chemistry Singlet oxygen Sclareol Organic Chemistry Organische Chemie 0104 chemical sciences chemistry (&/-)-isodrimenin derivatives Photooxygenation Stereoselectivity efficient synthesis drimane-related sesquiterpenes |
| Zdroj: | Tetrahedron, 69(2), 918-926 Tetrahedron 69 (2013) 2 |
| ISSN: | 0040-4020 |
| Popis: | Starting from (+)-larixol and (-)-sclareol, new syntheses of (+)-6-ketoeuryfuran, (+)-6-ketowinterin, and (-)-7-ketoeuryfuran have been elaborated in high yields. (+)-6-Ketowinterin was synthesized for the first time. Both euryfurans are excellent starting materials for the synthesis of important polyfunctional biologically active drimanic compounds. (C) 2012 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect