Impact of educational level on incident chronic kidney disease during 13 years of follow-up: a prospective cohort study
| Autor: | R. Ghodssi-Ghassemabadi, F Azizi, Parisa Amiri, Farzad Hadaegh, Niloofar Barzegar, Maryam Tohidi |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Population Renal function Iran 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Medicine Humans 030212 general & internal medicine Prospective Studies Renal Insufficiency Chronic Prospective cohort study education Survival analysis education.field_of_study business.industry 030503 health policy & services Incidence Hazard ratio Public Health Environmental and Occupational Health General Medicine medicine.disease Confidence interval Population study Educational Status 0305 other medical science business Kidney disease |
| Zdroj: | Public health. 195 |
| ISSN: | 1476-5616 |
| Popis: | Objectives To examine the association between educational level and chronic kidney disease (CKD) among the Iranian population. Study design This is a prospective cohort study conducted in the framework of the Tehran Lipid and Glucose Study. Methods A total of 8173 Iranians (men = 3659) aged ≥20 years were included in the study. CKD was defined as estimated glomerular filtration rate (eGFR) Results During a median follow-up of 13.14 years, 2609 cases of incident CKD were identified; the corresponding incidence rate was 26.35 (range 25.39–27.34) per 1000 person-years. Compared to low educational level, middle and high educational levels showed lower risks for incident CKD in the crude model [hazard ratio (HR) 0.37 (95% confidence interval {CI} 0.34–0.40) and HR 0.40 (95% CI 0.35–0.45), respectively]; however, these HRs changed direction after further adjustment for age and gender [HR 1.26 (95% CI 1.14–1.39) and HR 1.40 (95% CI 1.22–1.61), respectively]. The increased risk of incident CKD for those at higher educational levels remained significant in the fully adjusted model. In addition, results from the gender stratified analyses were in the same direction as those found among the whole study population (P-value for interaction of gender and education >0.8). Conclusions Higher educational levels were associated with incident CKD during more than a decade of follow-up; this finding may be attributed to unhealthy lifestyle behaviours among this population group. |
| Databáze: | OpenAIRE |
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